This is the fourteenth in a series of profiles about recent NIH postdocs who have found an array of jobs, from academia to industry to communications and beyond, in the U.S. and abroad. What do they do now, and how did they get there? What challenges did they face, and what advice do they have? Read on to find out.
Name: Michael Abram
Current position: Research scientist, Gilead Sciences, Inc.
Location: Foster City,CA
Time in current position: 11 months
Postdoc: Fidelity of HIV-1 replication with Stephen Hughes at NCI-Frederick
Day-to-day: I work in clinical virology. It’s about 50 percent scientific research, filling in knowledge gaps about HIV drugs that are soon to be FDA-approved or have recently been approved. My research focus is on understanding mechanisms of action and resistance to these drugs, and how they work in combination as antivirals. The remaining half of my job involves nonclinical regulatory work, such as contributing to new drug applications to the FDA and providing clinical virology support on Phase III studies for drugs that will soon be approved. This latter part of my job involves assessing resistance mutations that may be arising in human subjects and determining the effectiveness of these drugs compared to the current standard of care.
It’s always a balancing act. Spending time on one thing usually takes away from another. But while there never seems to be enough time, and there is frequently a sense of urgency to some responsibilities, I am really enjoying my job. No day is the same. I have brought new insights and fresh perspective, which is one of the qualities they were looking for. For the most part I’m allowed creative freedom in my position when around me there is a lot of repetition.